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Probing High Affinity Sequences of DNA Aptamer against VEGF(165)
Vascular endothelial growth factor (VEGF(165)) is a potent angiogenic mitogen commonly overexpressed in cancerous cells. It contains two main binding domains, the receptor-binding domain (RBD) and the heparin-binding domain (HBD). This study attempted to identify the specific sequences of the VEa5 D...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281051/ https://www.ncbi.nlm.nih.gov/pubmed/22359573 http://dx.doi.org/10.1371/journal.pone.0031196 |