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No Differential Regulation of Dopamine Transporter (DAT) and Vesicular Monoamine Transporter 2 (VMAT2) Binding in a Primate Model of Parkinson Disease

Radioligands for DAT and VMAT2 are widely used presynaptic markers for assessing dopamine (DA) nerve terminals in Parkinson disease (PD). Previous in vivo imaging and postmortem studies suggest that these transporter sites may be regulated as the numbers of nigrostriatal neurons change in pathologic...

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Detalles Bibliográficos
Autores principales: Tian, LinLin, Karimi, Morvarid, Loftin, Susan K., Brown, Chris A., Xia, HuChuan, Xu, JinBin, Mach, Robert H., Perlmutter, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281061/
https://www.ncbi.nlm.nih.gov/pubmed/22359591
http://dx.doi.org/10.1371/journal.pone.0031439