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Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum
BACKGROUND: Plasmodium falciparum, the causative agent of human malaria, expresses two aminopeptidases, PfM1AAP and PfM17LAP, critical to generating a free amino acid pool used by the intraerythrocytic stage of the parasite for proteins synthesis, growth and development. These exopeptidases are pote...
Autores principales: | Poreba, Marcin, McGowan, Sheena, Skinner-Adams, Tina S., Trenholme, Katharine R., Gardiner, Donald L., Whisstock, James C., To, Joyce, Salvesen, Guy S., Dalton, John P., Drag, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281095/ https://www.ncbi.nlm.nih.gov/pubmed/22359643 http://dx.doi.org/10.1371/journal.pone.0031938 |
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