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ARF1 and GBF1 Generate a PI4P-Enriched Environment Supportive of Hepatitis C Virus Replication

Cellular levels of phosphatidylinositol 4-phosphate (PI4P) have been shown to be upregulated during RNA replication of several viruses, including the HCV replicon model. However, whether PI4P is required in an infectious HCV model remains unknown. Moreover, it is not established whether the host tra...

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Detalles Bibliográficos
Autores principales: Zhang, Leiliang, Hong, Zhi, Lin, Wenyu, Shao, Run-Xuan, Goto, Kaku, Hsu, Victor W., Chung, Raymond T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281116/
https://www.ncbi.nlm.nih.gov/pubmed/22359663
http://dx.doi.org/10.1371/journal.pone.0032135