Cargando…

Dynamic regulation of glucocorticoid signalling in health and disease

Activation of the glucocorticoid receptor (GR) by endogenous and synthetic glucocorticoids regulates hundreds of genes to control regulatory networks in development, metabolism, cognition and inflammation. Elucidation of the mechanisms that regulate glucocorticoid action has highlighted the dynamic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Biddie, Simon C., Conway-Campbell, Becky L., Lightman, Stafford L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281495/ https://www.ncbi.nlm.nih.gov/pubmed/21891790 http://dx.doi.org/10.1093/rheumatology/ker215

Ejemplares similares

Dynamics of ACTH and Cortisol Secretion and Implications for Disease
por: Lightman, Stafford L, et al.
Publicado: (2020)

The emerging importance of ultradian glucocorticoid rhythms within metabolic pathology
por: Flynn, Benjamin P., et al.
Publicado: (2018)

Glucocorticoid Receptor–Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses
por: Rivers, Caroline A, et al.
Publicado: (2019)

The HSP90 Molecular Chaperone Cycle Regulates Cyclical Transcriptional Dynamics of the Glucocorticoid Receptor and Its Coregulatory Molecules CBP/p300 During Ultradian Ligand Treatment
por: Conway-Campbell, Becky L., et al.
Publicado: (2011)

Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility
por: Gjerstad, Julia K, et al.
Publicado: (2018)

Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo
por: George, Charlotte L., et al.
Publicado: (2017)

Phase-shifting the circadian glucocorticoid profile induces disordered feeding behaviour by dysregulating hypothalamic neuropeptide gene expression
por: Yoshimura, Mitsuhiro, et al.
Publicado: (2023)

Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver
por: Flynn, Benjamin P., et al.
Publicado: (2021)

Characterizing Dynamic Interactions between Ultradian Glucocorticoid Rhythmicity and Acute Stress Using the Phase Response Curve
por: Rankin, James, et al.
Publicado: (2012)

Prolonged treatment with the synthetic glucocorticoid methylprednisolone affects adrenal steroidogenic function and response to inflammatory stress in the rat
por: Spiga, Francesca, et al.
Publicado: (2020)

The Origin of Glucocorticoid Hormone Oscillations
por: Walker, Jamie J., et al.
Publicado: (2012)

Subcutaneous pulsatile glucocorticoid replacement therapy
por: Russell, Georgina M, et al.
Publicado: (2014)

Time of day influences stress hormone response to ketamine
por: Birnie, Matthew T., et al.
Publicado: (2022)

The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids
por: Oster, Henrik, et al.
Publicado: (2016)

Desipramine treatment has minimal effects on the brain accumulation of glucocorticoids in P-gp-deficient and wild-type mice
por: Mason, Brittany L., et al.
Publicado: (2011)

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
por: John, Sam, et al.
Publicado: (2011)

Rapid intra-adrenal feedback regulation of glucocorticoid synthesis
por: Walker, J. J., et al.
Publicado: (2015)

Dynamics of ACTH-Mediated Regulation of Gene Transcription in ATC1 and ATC7 Adrenal Zona Fasciculata Cell Lines
por: Hazell, Georgina, et al.
Publicado: (2019)

Acute Glucocorticoid Administration Rapidly Suppresses Basal and Stress-Induced Hypothalamo-Pituitary-Adrenal Axis Activity
por: Andrews, Marcus H., et al.
Publicado: (2012)

Circadian and Ultradian Rhythms of Free Glucocorticoid Hormone Are Highly Synchronized between the Blood, the Subcutaneous Tissue, and the Brain
por: Qian, Xiaoxiao, et al.
Publicado: (2012)

The Importance of Biological Oscillators for Hypothalamic-Pituitary-Adrenal Activity and Tissue Glucocorticoid Response: Coordinating Stress and Neurobehavioural Adaptation
por: Russell, G M, et al.
Publicado: (2015)

Pulsatility of glucocorticoid hormones in pregnancy: Changes with gestation and obesity
por: Stirrat, Laura I., et al.
Publicado: (2018)

From bedside to bench: regulation of host factors in SARS-CoV-2 infection
por: Ong, Samantha Y. Q., et al.
Publicado: (2021)

Temporal Effect of Adrenocorticotrophic Hormone on Adrenal Glucocorticoid Steroidogenesis: Involvement of the Transducer of Regulated Cyclic AMP-Response Element-Binding Protein Activity
por: Spiga, F, et al.
Publicado: (2011)

Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation
por: Stubbs, Felicity E., et al.
Publicado: (2022)

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA
por: Pooley, John R., et al.
Publicado: (2020)

Involvement of CREB-regulated transcription coactivators (CRTC) in transcriptional activation of steroidogenic acute regulatory protein (Star) by ACTH
por: Smith, Lorna I.F., et al.
Publicado: (2020)

Circadian regulation of hippocampal function is disrupted with corticosteroid treatment
por: Birnie, Matthew T., et al.
Publicado: (2023)

Glucocorticoid ultradian rhythmicity differentially regulates mood and resting state networks in the human brain: A randomised controlled clinical trial
por: Kalafatakis, Konstantinos, et al.
Publicado: (2021)

The Glucocorticoid Receptor in Cardiovascular Health and Disease
por: Liu, Bing, et al.
Publicado: (2019)

The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease
por: Fries, Gabriel R., et al.
Publicado: (2017)

Glucocorticoid Receptor Signaling in Diabetes
por: Kokkinopoulou, Ioanna, et al.
Publicado: (2021)

Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways
por: Sevilla, Lisa M., et al.
Publicado: (2021)

The glucocorticoid receptor signalling in breast cancer
por: Moutsatsou, Paraskevi, et al.
Publicado: (2008)

Steroids in paediatric heart surgery: eminence or evidence-based practice?
por: Fudulu, Daniel, et al.
Publicado: (2018)

Genome-Wide Identification of Basic Helix–Loop–Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus
por: Pooley, John R., et al.
Publicado: (2017)

Regulation of triglyceride metabolism by glucocorticoid receptor
por: Wang, Jen-Chywan, et al.
Publicado: (2012)

Glucocorticoid-Induced Leucine Zipper (GILZ) in Cardiovascular Health and Disease
por: Cappetta, Donato, et al.
Publicado: (2021)

Wnt-Signaling Regulated by Glucocorticoid-Induced miRNAs
por: Butz, Henriett, et al.
Publicado: (2021)

The Role of Glucocorticoids in Inflammatory Diseases
por: Reichardt, Sybille D., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_itt2j97i5sdq37kpjpmso9ksgg