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Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase

Febrifugine, one of the fifty fundamental herbs of traditional Chinese medicine, has been characterized for its therapeutic activity whilst its molecular target has remained unknown. Febrifugine derivatives have been used to treat malaria, cancer, fibrosis, and inflammatory disease. We recently demo...

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Detalles Bibliográficos
Autores principales:	Keller, Tracy L., Zocco, Davide, Sundrud, Mark S., Hendrick, Margaret, Edenius, Maja, Yum, Jina, Kim, Yeon-Jin, Lee, Hak-kyo, Cortese, Joseph F., Wirth, Dyann, Dignam, John David, Rao, Anjana, Yeo, Chang-Yeol, Mazitschek, Ralph, Whitman, Malcolm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281520/ https://www.ncbi.nlm.nih.gov/pubmed/22327401 http://dx.doi.org/10.1038/nchembio.790

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