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Enhancers and silencers: an integrated and simple model for their function

Regulatory DNA elements such as enhancers, silencers and insulators are embedded in metazoan genomes, and they control gene expression during development. Although they fulfil different roles, they share specific properties. Herein we discuss some examples and a parsimonious model for their function...

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Detalles Bibliográficos
Autores principales: Kolovos, Petros, Knoch, Tobias A, Grosveld, Frank G, Cook, Peter R, Papantonis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281776/
https://www.ncbi.nlm.nih.gov/pubmed/22230046
http://dx.doi.org/10.1186/1756-8935-5-1