Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells

BACKGROUND: Colorectal carcinomas (CRC) carry massive genetic and transcriptional alterations that influence multiple cellular pathways. The study of proteins whose loss-of-function (LOF) alters the growth of CRC cells can be used to further understand the cellular processes cancer cells depend upon...

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Detalles Bibliográficos
Autores principales: Hummon, Amanda B, Pitt, Jason J, Camps, Jordi, Emons, Georg, Skube, Susan B, Huppi, Konrad, Jones, Tamara L, Beissbarth, Tim, Kramer, Frank, Grade, Marian, Difilippantonio, Michael J, Ried, Thomas, Caplen, Natasha J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281783/
https://www.ncbi.nlm.nih.gov/pubmed/22216762
http://dx.doi.org/10.1186/1476-4598-11-1

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