M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

BACKGROUND: In obesity, phenotypic switches occur in macrophage populations such that the predominantly M2-polarised anti-inflammatory state seen in lean individuals changes to a predominantly M1-polarised pro-inflammatory state in those who are obese. However, the mechanisms by which these phenotyp...

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Detalles Bibliográficos
Autores principales: Isa, Suleiman A, Ruffino, José S, Ahluwalia, Maninder, Thomas, Andrew W, Morris, Keith, Webb, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281809/
https://www.ncbi.nlm.nih.gov/pubmed/22146099
http://dx.doi.org/10.1186/1476-511X-10-229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281809/
https://www.ncbi.nlm.nih.gov/pubmed/22146099
http://dx.doi.org/10.1186/1476-511X-10-229

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