Novel Transgenic Mice for Inducible Gene Overexpression in Pancreatic Cells Define Glucocorticoid Receptor-Mediated Regulations of Beta Cells

Conditional gene deletion in specific cell populations has helped the understanding of pancreas development. Using this approach, we have shown that deleting the glucocorticoid receptor (GR) gene in pancreatic precursor cells leads to a doubled beta-cell mass. Here, we provide genetic tools that per...

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Detalles Bibliográficos
Autores principales: Blondeau, Bertrand, Sahly, Iman, Massouridès, Emmanuelle, Singh-Estivalet, Amrit, Valtat, Bérengère, Dorchene, Delphine, Jaisser, Frédéric, Bréant, Bernadette, Tronche, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281827/
https://www.ncbi.nlm.nih.gov/pubmed/22363422
http://dx.doi.org/10.1371/journal.pone.0030210

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