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cis-Expression QTL Analysis of Established Colorectal Cancer Risk Variants in Colon Tumors and Adjacent Normal Tissue

Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analyses to investigate possible regulatory functions o...

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Detalles Bibliográficos
Autores principales: Loo, Lenora W. M., Cheng, Iona, Tiirikainen, Maarit, Lum-Jones, Annette, Seifried, Ann, Dunklee, Lucas M., Church, James M., Gryfe, Robert, Weisenberger, Daniel J., Haile, Robert W., Gallinger, Steven, Duggan, David J., Thibodeau, Stephen N., Casey, Graham, Le Marchand, Loïc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281844/
https://www.ncbi.nlm.nih.gov/pubmed/22363440
http://dx.doi.org/10.1371/journal.pone.0030477