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MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State

Increasing evidence supports the involvement of microRNAs (miRNAs) in inflammatory and immune processes in prion neuropathogenesis. MiRNAs are small, non-coding RNA molecules which are emerging as key regulators of numerous cellular processes. We established miR-146a over-expression in prion-infecte...

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Detalles Bibliográficos
Autores principales:	Saba, Reuben, Gushue, Shantel, Huzarewich, Rhiannon L. C. H., Manguiat, Kathy, Medina, Sarah, Robertson, Catherine, Booth, Stephanie A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281888/ https://www.ncbi.nlm.nih.gov/pubmed/22363497 http://dx.doi.org/10.1371/journal.pone.0030832

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