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Differences in MEF2 and NFAT Transcriptional Pathways According to Human Heart Failure Aetiology

BACKGROUND: Ca(2+) handling machinery modulates the activation of cardiac transcription pathways involved in heart failure (HF). The present study investigated the effect of HF aetiology on Ca(+2) handling proteins and NFAT1, MEF2C and GATA4 (transcription factors) in the same cardiac tissue. METHOD...

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Detalles Bibliográficos
Autores principales: Cortés, Raquel, Rivera, Miguel, Roselló-Lletí, Esther, Martínez-Dolz, Luis, Almenar, Luis, Azorín, Inmaculada, Lago, Francisca, González-Juanatey, José Ramón, Portolés, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281902/
https://www.ncbi.nlm.nih.gov/pubmed/22363514
http://dx.doi.org/10.1371/journal.pone.0030915