Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization

An ingenious system evolved to facilitate insulin binding to the insulin receptor as a monomer and at the same time ensure sufficient stability of insulin during storage. Insulin dimer is the cornerstone of this system. Insulin dimer is relatively weak, which ensures dissociation into monomers in th...

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Detalles Bibliográficos
Autores principales: Vinther, Tine N., Norrman, Mathias, Strauss, Holger M., Huus, Kasper, Schlein, Morten, Pedersen, Thomas Å., Kjeldsen, Thomas, Jensen, Knud J., Hubálek, František
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281904/
https://www.ncbi.nlm.nih.gov/pubmed/22363506
http://dx.doi.org/10.1371/journal.pone.0030882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281904/
https://www.ncbi.nlm.nih.gov/pubmed/22363506
http://dx.doi.org/10.1371/journal.pone.0030882

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