Cargando…
Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization
An ingenious system evolved to facilitate insulin binding to the insulin receptor as a monomer and at the same time ensure sufficient stability of insulin during storage. Insulin dimer is the cornerstone of this system. Insulin dimer is relatively weak, which ensures dissociation into monomers in th...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281904/ https://www.ncbi.nlm.nih.gov/pubmed/22363506 http://dx.doi.org/10.1371/journal.pone.0030882 |