Cargando…

Exendin-4 Improves Steatohepatitis by Increasing Sirt1 Expression in High-Fat Diet-Induced Obese C57BL/6J Mice

The effects of exendin-4 on Sirt1 expression as a mechanism of reducing fatty liver have not been previously reported. Therefore, we investigated whether the beneficial effects of exendin-4 treatment on fatty liver are mediated via Sirt1 in high-fat (HF) diet-induced obese C57BL/6J mice and related...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jinmi, Hong, Seok-Woo, Chae, Seoung Wan, Kim, Dong Hoon, Choi, Ji Hun, Bae, Ji Cheol, Park, Se Eun, Rhee, Eun-Jung, Park, Cheol-Young, Oh, Ki-Won, Park, Sung-Woo, Kim, Sun-Woo, Lee, Won-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281956/ https://www.ncbi.nlm.nih.gov/pubmed/22363635 http://dx.doi.org/10.1371/journal.pone.0031394

Ejemplares similares

Exendin-4 Inhibits Hepatic Lipogenesis by Increasing β-Catenin Signaling
por: Seo, Mi Hae, et al.
Publicado: (2016)

Exendin-4 Inhibits the Expression of SEPP1 and Fetuin-A via Improvement of Palmitic Acid-Induced Endoplasmic Reticulum Stress by AMPK
por: Lee, Jinmi, et al.
Publicado: (2015)

Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats
por: Yang, Soo Jin, et al.
Publicado: (2011)

Activation of AMP-Activated Protein Kinase Attenuates Tumor Necrosis Factor-α-Induced Lipolysis via Protection of Perilipin in 3T3-L1 Adipocytes
por: Hong, Seok-Woo, et al.
Publicado: (2014)

Deficiency of Sphingosine-1-Phosphate Reduces the Expression of Prohibitin and Causes β-Cell Impairment via Mitochondrial Dysregulation
por: Hong, Seok-Woo, et al.
Publicado: (2018)

Combined Effect of Nonalcoholic Fatty Liver Disease and Impaired Fasting Glucose on the Development of Type 2 Diabetes: A 4-year retrospective longitudinal study
por: Bae, Ji Cheol, et al.
Publicado: (2011)

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
por: Hong, Seok-Woo, et al.
Publicado: (2018)

The Association of Unintentional Changes in Weight, Body Composition, and Homeostasis Model Assessment Index with Glycemic Progression in Non-Diabetic Healthy Subjects
por: Rhee, Eun-Jung, et al.
Publicado: (2011)

Higher incidence of sperm granuloma in the epididymis of C57BL/6N mice
por: Park, Do-Yong, et al.
Publicado: (2018)

Predictive Value of Triglyceride Glucose Index for the Risk of Incident Diabetes: A 4-Year Retrospective Longitudinal Study
por: Lee, Da Young, et al.
Publicado: (2016)

Metabolic Health Is a More Important Determinant for Diabetes Development than Simple Obesity: A 4-Year Retrospective Longitudinal Study
por: Rhee, Eun-Jung, et al.
Publicado: (2014)

Urinary adiponectin concentration is positively associated with micro- and macro-vascular complications
por: Jeon, Won Seon, et al.
Publicado: (2013)

Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources
por: Yun, Woo Bin, et al.
Publicado: (2017)

The Association of Brachial-Ankle Pulse Wave Velocity with 30-Minute Post-Challenge Plasma Glucose Levels in Korean Adults with No History of Type 2 Diabetes
por: Choi, Eun-Suk, et al.
Publicado: (2010)

Increased risk for development of coronary artery calcification in subjects with non-alcoholic fatty liver disease and systemic inflammation
por: Kim, Jihyun, et al.
Publicado: (2017)

Erratum: Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources
por: Yun, Woo Bin, et al.
Publicado: (2017)

Retrospective Analysis on the Efficacy, Safety and Treatment Failure Group of Sitagliptin for Mean 10-Month Duration
por: Kim, Won Jun, et al.
Publicado: (2011)

Serum 1,5-Anhydroglucitol Concentrations Are a Reliable Index of Glycemic Control in Type 2 Diabetes With Mild or Moderate Renal Dysfunction
por: Kim, Won Jun, et al.
Publicado: (2012)

Immunological distinctions between nonalcoholic steatohepatitis and hepatocellular carcinoma
por: Koo, Seo-Young, et al.
Publicado: (2020)

Association of Serum Adipocyte-Specific Fatty Acid Binding Protein with Fatty Liver Index as a Predictive Indicator of Nonalcoholic Fatty Liver Disease
por: Jeon, Won Seon, et al.
Publicado: (2013)

Regular Exercise Is Associated with a Reduction in the Risk of NAFLD and Decreased Liver Enzymes in Individuals with NAFLD Independent of Obesity in Korean Adults
por: Bae, Ji Cheol, et al.
Publicado: (2012)

Waist Circumference as a Marker of Obesity Is More Predictive of Coronary Artery Calcification than Body Mass Index in Apparently Healthy Korean Adults: The Kangbuk Samsung Health Study
por: Park, Jongsin, et al.
Publicado: (2016)

Metabolic syndrome criteria as predictors of subclinical atherosclerosis based on the coronary calcium score
por: Seo, Mi Hae, et al.
Publicado: (2015)

Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice
por: Yun, Woo Bin, et al.
Publicado: (2021)

Deletion of NKX3.1 via CRISPR/Cas9 Induces Prostatic Intraepithelial Neoplasia in C57BL/6 Mice
por: Park, Jin Ju, et al.
Publicado: (2020)

Tumor Necrosis Factor-α as a Predictor for the Development of Nonalcoholic Fatty Liver Disease: A 4-Year Follow-Up Study
por: Seo, Yun Yong, et al.
Publicado: (2013)

Dulaglutide Ameliorates Palmitic Acid-Induced Hepatic Steatosis by Activating FAM3A Signaling Pathway
por: Lee, Jinmi, et al.
Publicado: (2022)

Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells
por: Hong, Seok-Woo, et al.
Publicado: (2020)

Association of Waist-Height Ratio with Diabetes Risk: A 4-Year Longitudinal Retrospective Study
por: Son, Yoon Jeong, et al.
Publicado: (2016)

The Risk of Metabolic Syndrome According to the White Blood Cell Count in Apparently Healthy Korean Adults
por: Jung, Chan-Hee, et al.
Publicado: (2013)

Metabolic Health Is More Closely Associated with Coronary Artery Calcification than Obesity
por: Rhee, Eun-Jung, et al.
Publicado: (2013)

Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice
por: Han, Seung Jin, et al.
Publicado: (2016)

The relationship between serum fatty-acid binding protein 4 level and lung function in Korean subjects with normal ventilatory function
por: Park, Hye-Jeong, et al.
Publicado: (2016)

C-Peptide-Based Index Is More Related to Incident Type 2 Diabetes in Non-Diabetic Subjects than Insulin-Based Index
por: Kim, Jong-Dai, et al.
Publicado: (2016)

Higher association of coronary artery calcification with non-alcoholic fatty liver disease than with abdominal obesity in middle-aged Korean men: the Kangbuk Samsung Health Study
por: Lee, Min-Kyung, et al.
Publicado: (2015)

Insulin resistance contributes more to the increased risk for diabetes development in subjects with low lipoprotein(a) level than insulin secretion
por: Rhee, Eun-Jung, et al.
Publicado: (2017)

GLP-1 Receptor Agonist and Non-Alcoholic Fatty Liver Disease
por: Lee, Jinmi, et al.
Publicado: (2012)

The Relationship of Adiponectin/Leptin Ratio with Homeostasis Model Assessment Insulin Resistance Index and Metabolic Syndrome in Apparently Healthy Korean Male Adults
por: Jung, Chan-Hee, et al.
Publicado: (2010)

SAT-634 The Effect of Continine Verified Smoking on the Development of Diabetes
por: Jung, Inha, et al.
Publicado: (2020)

Autonomic Imbalance Increases the Risk for Non-alcoholic Fatty Liver Disease
por: Jung, Inha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nn18jmare4cek3iqpn4tpqfgaa