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α(1)Proteinase Inhibitor Regulates CD4(+) Lymphocyte Levels and Is Rate Limiting in HIV-1 Disease

BACKGROUND: The regulation of adult stem cell migration through human hematopoietic tissue involves the chemokine CXCL12 (SDF-1) and its receptor CXCR4 (CD184). In addition, human leukocyte elastase (HLE) plays a key role. When HLE is located on the cell surface (HLE(CS)), it acts not as a proteinas...

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Detalles Bibliográficos
Autores principales:	Bristow, Cynthia L., Babayeva, Mariya A., LaBrunda, Michelle, Mullen, Michael P., Winston, Ronald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281957/ https://www.ncbi.nlm.nih.gov/pubmed/22363634 http://dx.doi.org/10.1371/journal.pone.0031383

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