Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

Mutations in the TP53 gene commonly result in the expression of a full-length protein that drives cancer cell invasion and metastasis. Herein, we have deciphered the global landscape of transcriptional regulation by mutant p53 through the application of a panel of isogenic H1299 derivatives with ind...

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Detalles Bibliográficos
Autores principales: Neilsen, Paul M., Noll, Jacqueline E., Suetani, Rachel J., Schulz, Renee B., Al-Ejeh, Fares, Evdokiou, Andreas, Lane, David P., Callen, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282078/
https://www.ncbi.nlm.nih.gov/pubmed/22203497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282078/
https://www.ncbi.nlm.nih.gov/pubmed/22203497

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