A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA)

We have developed a modular scaffold for preparing high-affinity, homo-multivalent inhibitors of the prostate-specific membrane antigen (PSMA) for imaging and therapy of prostate cancer (PCa). Our system contains a lysine-based (∝-, ε-) dialkyne residue for incorporating a PSMA binding Lys-Glu urea...

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Detalles Bibliográficos
Autores principales: Banerjee, Sangeeta Ray, Pullambhatla, Mrudula, Shallal, Hassan, Lisok, Ala, Mease, Ronnie C., Pomper, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282081/
https://www.ncbi.nlm.nih.gov/pubmed/22207391

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