Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1

Selenium compounds are known as cancer preventive agents and are also able to ameliorate the toxicity associated with anti-cancer radiation and chemotherapy in mouse models. Sensitivity to the toxicity of chemotherapy is also modulated by the circadian clock, molecular time-keeping system that under...

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Detalles Bibliográficos
Autores principales: Hu, Yan, Spengler, Mary L., Kuropatwinski, Karen K., Comas, Maria, Jackson, Marilyn, Chernov, Mikhail V., Gleiberman, Anatoly S., Fedtsova, Natalia, Rustum, Youcef M., Gudkov, Andrei V., Antoch, Marina P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282084/
https://www.ncbi.nlm.nih.gov/pubmed/22249125

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