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Blockade of ERK Phosphorylation in the Nucleus Accumbens Inhibits the Expression of Cocaine-induced Behavioral Sensitization in Rats

Repeated administration of psychostimulants such as cocaine leads to the development of behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in such effects of these drugs. Although the nucleus accumbens (NA...

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Detalles Bibliográficos
Autores principales: Kim, Seungwoo, Shin, Joong-Keun, Yoon, Hyung Shin, Kim, Jeong-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282227/
https://www.ncbi.nlm.nih.gov/pubmed/22359477
http://dx.doi.org/10.4196/kjpp.2011.15.6.389