Apparent clearance of valproic acid in elderly epileptic patients: estimation of the confounding effect of albumin concentration

BACKGROUND. Valproic acid (VPA) apparent clearance (CL) estimated from total serum concentrations is analogous in elderly and non-elderly adult patients. As drug–protein binding decreases in old age, the aim of our study was to evaluate the confounding effect of the serum albumin concentration on th...

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Detalles Bibliográficos
Autores principales: Lampon, Natalia, Tutor, J. Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282241/
https://www.ncbi.nlm.nih.gov/pubmed/22206465
http://dx.doi.org/10.3109/03009734.2011.640412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282241/
https://www.ncbi.nlm.nih.gov/pubmed/22206465
http://dx.doi.org/10.3109/03009734.2011.640412

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