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High-pressure-induced water penetration into 3-isopropylmalate dehydrogenase
Hydrostatic pressure induces structural changes in proteins, including denaturation, the mechanism of which has been attributed to water penetration into the protein interior. In this study, structures of 3-isopropylmalate dehydrogenase (IPMDH) from Shewanella oneidensis MR-1 were determined at abou...
Autores principales: | Nagae, Takayuki, Kawamura, Takashi, Chavas, Leonard M. G., Niwa, Ken, Hasegawa, Masashi, Kato, Chiaki, Watanabe, Nobuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282623/ https://www.ncbi.nlm.nih.gov/pubmed/22349232 http://dx.doi.org/10.1107/S0907444912001862 |
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