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Correlation between promoter methylation of p14(ARF), TMS1/ASC, and DAPK, and p53 mutation with prognosis in cholangiocarcinoma

BACKGROUND: To study the methylation status of genes that play a role in the p53-Bax mitochondrial apoptosis pathway and its clinical significance in cholangiocarcinoma. PATIENTS AND METHODS: Out of 36 cases cholangiocarcinoma patients from April 2000 to May 2005 were collected.Promoter hypermethyla...

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Detalles Bibliográficos
Autores principales: Xiaofang, Liu, Kun, Tang, Shaoping, Yu, Zaiqiu, Wang, Hailong, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282663/
https://www.ncbi.nlm.nih.gov/pubmed/22230750
http://dx.doi.org/10.1186/1477-7819-10-5