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Transcriptional Repressor NIR Functions in the Ribosome RNA Processing of Both 40S and 60S Subunits

BACKGROUND: NIR was identified as an inhibitor of histone acetyltransferase and it represses transcriptional activation of p53. NIR is predominantly localized in the nucleolus and known as Noc2p, which is involved in the maturation of the 60S ribosomal subunit. However, how NIR functions in the nucl...

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Detalles Bibliográficos
Autores principales: Wu, Jianguo, Zhang, Ying, Wang, Yingshuang, Kong, Ruirui, Hu, Lelin, Schuele, Roland, Du, Xiaojuan, Ke, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282729/
https://www.ncbi.nlm.nih.gov/pubmed/22363708
http://dx.doi.org/10.1371/journal.pone.0031692

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