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RHGF-2 Is an Essential Rho-1 Specific RhoGEF that binds to the Multi-PDZ Domain Scaffold Protein MPZ-1 in Caenorhabditis elegans

RhoGEF proteins activate the Rho family of small GTPases and thus play a key role in regulating fundamental cellular processes such as cell morphology and polarity, cell cycle progression and gene transcription. We identified a Caenorhabditis elegans RhoGEF protein, RHGF-2, as a binding partner of t...

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Detalles Bibliográficos
Autores principales: Lin, Li, Tran, Thuy, Hu, Shuang, Cramer, Todd, Komuniecki, Richard, Steven, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282746/
https://www.ncbi.nlm.nih.gov/pubmed/22363657
http://dx.doi.org/10.1371/journal.pone.0031499

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