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RHGF-2 Is an Essential Rho-1 Specific RhoGEF that binds to the Multi-PDZ Domain Scaffold Protein MPZ-1 in Caenorhabditis elegans
RhoGEF proteins activate the Rho family of small GTPases and thus play a key role in regulating fundamental cellular processes such as cell morphology and polarity, cell cycle progression and gene transcription. We identified a Caenorhabditis elegans RhoGEF protein, RHGF-2, as a binding partner of t...
Autores principales: | Lin, Li, Tran, Thuy, Hu, Shuang, Cramer, Todd, Komuniecki, Richard, Steven, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282746/ https://www.ncbi.nlm.nih.gov/pubmed/22363657 http://dx.doi.org/10.1371/journal.pone.0031499 |
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