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Toward Low-Cost Affinity Reagents: Lyophilized Yeast-scFv Probes Specific for Pathogen Antigens
The generation of affinity reagents, usually monoclonal antibodies, remains a critical bottleneck in biomedical research and diagnostic test development. Recombinant antibody-like proteins such as scFv have yet to replace traditional monoclonal antibodies in antigen detection applications, in large...
Autores principales: | Gray, Sean A., Weigel, Kris M., Ali, Ibne K. M., Lakey, Annie A., Capalungan, Jeremy, Domingo, Gonzalo J., Cangelosi, Gerard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282784/ https://www.ncbi.nlm.nih.gov/pubmed/22363793 http://dx.doi.org/10.1371/journal.pone.0032042 |
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