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Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells

BACKGROUND: The sestrin family of stress-responsive genes (SESN1-3) are suggested to be involved in regulation of metabolism and aging through modulation of the AMPK-mTOR pathway. AMP-activated protein kinase (AMPK) is an effector of the tumour suppressor LKB1, which regulates energy homeostasis, ce...

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Detalles Bibliográficos
Autores principales:	Sanli, Toran, Linher-Melville, Katja, Tsakiridis, Theodoros, Singh, Gurmit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282792/ https://www.ncbi.nlm.nih.gov/pubmed/22363791 http://dx.doi.org/10.1371/journal.pone.0032035

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