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Bmi-1 Absence Causes Premature Brain Degeneration

Bmi-1, a polycomb transcriptional repressor, is implicated in cell cycle regulation and cell senescence. Its absence results in generalized astrogliosis and epilepsy during the postnatal development, but the underlying mechanisms are poorly understood. Here, we demonstrate the occurrence of oxidativ...

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Detalles Bibliográficos
Autores principales:	Cao, Guangliang, Gu, Minxia, Zhu, Min, Gao, Junying, Yin, Ying, Marshall, Charles, Xiao, Ming, Ding, Jiong, Miao, Dengshun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282795/ https://www.ncbi.nlm.nih.gov/pubmed/22363787 http://dx.doi.org/10.1371/journal.pone.0032015

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