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Age-Related Impairment in Insulin Release: The Essential Role of β(2)-Adrenergic Receptor

In this study, we investigated the significance of β(2)-adrenergic receptor (β(2)AR) in age-related impaired insulin secretion and glucose homeostasis. We characterized the metabolic phenotype of β(2)AR-null C57Bl/6N mice (β(2)AR(−/−)) by performing in vivo and ex vivo experiments. In vitro assays i...

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Detalles Bibliográficos
Autores principales:	Santulli, Gaetano, Lombardi, Angela, Sorriento, Daniela, Anastasio, Antonio, Del Giudice, Carmine, Formisano, Pietro, Béguinot, Francesco, Trimarco, Bruno, Miele, Claudia, Iaccarino, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282797/ https://www.ncbi.nlm.nih.gov/pubmed/22315324 http://dx.doi.org/10.2337/db11-1027

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