Evidence for Early Defects in Insulin Sensitivity and Secretion Before the Onset of Glucose Dysregulation in Obese Youths : A Longitudinal Study

We sought to determine whether obese adolescents with high-“normal” 2-h post-oral glucose tolerance test glucose levels display defects in insulin secretion and sensitivity associated with future development of impaired glucose tolerance (IGT). Insulin sensitivity was measured by hyperinsulinemic-eu...

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Detalles Bibliográficos
Autores principales: Giannini, Cosimo, Weiss, Ram, Cali, Anna, Bonadonna, Riccardo, Santoro, Nicola, Pierpont, Bridget, Shaw, Melissa, Caprio, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282810/
https://www.ncbi.nlm.nih.gov/pubmed/22315322
http://dx.doi.org/10.2337/db11-1111

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