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Effect of Dosing Interval Duration of Intermittent Ibandronate Treatment on the Healing Process of Femoral Osteotomy in a Rat Fracture Model

The effects of bisphosphonate treatment schedule on fracture healing have not previously been tested. We evaluated the effect of ibandronate dosing interval duration on healing following surgical “fracture” (osteotomy) using a rat femoral fracture model. Six-week-old rats (n = 160) underwent osteoto...

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Detalles Bibliográficos
Autores principales: Manabe, Takeshi, Mori, Satoshi, Mashiba, Tasuku, Kaji, Yoshio, Iwata, Ken, Komatsubara, Satoshi, Yamamoto, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282908/
https://www.ncbi.nlm.nih.gov/pubmed/22249523
http://dx.doi.org/10.1007/s00223-011-9563-4