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Effect of Dosing Interval Duration of Intermittent Ibandronate Treatment on the Healing Process of Femoral Osteotomy in a Rat Fracture Model
The effects of bisphosphonate treatment schedule on fracture healing have not previously been tested. We evaluated the effect of ibandronate dosing interval duration on healing following surgical “fracture” (osteotomy) using a rat femoral fracture model. Six-week-old rats (n = 160) underwent osteoto...
Autores principales: | Manabe, Takeshi, Mori, Satoshi, Mashiba, Tasuku, Kaji, Yoshio, Iwata, Ken, Komatsubara, Satoshi, Yamamoto, Tetsuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282908/ https://www.ncbi.nlm.nih.gov/pubmed/22249523 http://dx.doi.org/10.1007/s00223-011-9563-4 |
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