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The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study
INTRODUCTION: Lymphoid malignancies compose a wide spectrum of different morphologic and clinical syndromes known to vary widely throughout the world. The purpose of this study is to determine the prevalence and time trends of lymphoid malignancies. METHODS: A 15 (May 1st 1996-April 30th 2010) years...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The African Field Epidemiology Network
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283024/ https://www.ncbi.nlm.nih.gov/pubmed/22368753 |
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author | Omoti, Caroline Edijana Nwannadi, Alexander Ikenna Obieche, Jude Chike Olu-Eddo, Adesuwa Noma |
author_facet | Omoti, Caroline Edijana Nwannadi, Alexander Ikenna Obieche, Jude Chike Olu-Eddo, Adesuwa Noma |
author_sort | Omoti, Caroline Edijana |
collection | PubMed |
description | INTRODUCTION: Lymphoid malignancies compose a wide spectrum of different morphologic and clinical syndromes known to vary widely throughout the world. The purpose of this study is to determine the prevalence and time trends of lymphoid malignancies. METHODS: A 15 (May 1st 1996-April 30th 2010) years study of all patients who had lymph node biopsy at the Department of Haematology and Pathology, University of Benin Teaching Hospital, Benin City, Nigeria. RESULTS: The 391 patients had a male preponderance (M:F; 1.6:1). An increase in the lymphoid malignant cases was noted from 95 cases in the first 5-year interval (1996–2000) to 179 cases in the last 5-year interval (2006–2010) giving an average increase of 84.0%. Non-Hodgkins lymphoma (61.1%) and chronic lymphocytic leukaemia (18.2%) were the most frequent followed by Hodgkin's lymphoma and myeloma with equal proportions of 9.0% each. A positive correlation with a significant linear trends was obtained (r=0.1949, p<0.0001). Geographic areas at risk were found mainly in patients residing in Delta State (67.0%) which is a major oil producing state and Edo State (30.4%) where the hospital is located, both in the Niger Delta Region of Nigeria. CONCLUSION: Future research into environmental agents and genetic makeup/HLA typing of patients can be carried out. |
format | Online Article Text |
id | pubmed-3283024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-32830242012-02-24 The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study Omoti, Caroline Edijana Nwannadi, Alexander Ikenna Obieche, Jude Chike Olu-Eddo, Adesuwa Noma Pan Afr Med J Research INTRODUCTION: Lymphoid malignancies compose a wide spectrum of different morphologic and clinical syndromes known to vary widely throughout the world. The purpose of this study is to determine the prevalence and time trends of lymphoid malignancies. METHODS: A 15 (May 1st 1996-April 30th 2010) years study of all patients who had lymph node biopsy at the Department of Haematology and Pathology, University of Benin Teaching Hospital, Benin City, Nigeria. RESULTS: The 391 patients had a male preponderance (M:F; 1.6:1). An increase in the lymphoid malignant cases was noted from 95 cases in the first 5-year interval (1996–2000) to 179 cases in the last 5-year interval (2006–2010) giving an average increase of 84.0%. Non-Hodgkins lymphoma (61.1%) and chronic lymphocytic leukaemia (18.2%) were the most frequent followed by Hodgkin's lymphoma and myeloma with equal proportions of 9.0% each. A positive correlation with a significant linear trends was obtained (r=0.1949, p<0.0001). Geographic areas at risk were found mainly in patients residing in Delta State (67.0%) which is a major oil producing state and Edo State (30.4%) where the hospital is located, both in the Niger Delta Region of Nigeria. CONCLUSION: Future research into environmental agents and genetic makeup/HLA typing of patients can be carried out. The African Field Epidemiology Network 2012-01-20 /pmc/articles/PMC3283024/ /pubmed/22368753 Text en © Caroline Edijana Omoti et al. http://creativecommons.org/licenses/by/2.0 The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Omoti, Caroline Edijana Nwannadi, Alexander Ikenna Obieche, Jude Chike Olu-Eddo, Adesuwa Noma The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study |
title | The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study |
title_full | The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study |
title_fullStr | The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study |
title_full_unstemmed | The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study |
title_short | The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study |
title_sort | epidemiological features of lymphoid malignancies in benin city, nigeria: a 15 years study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283024/ https://www.ncbi.nlm.nih.gov/pubmed/22368753 |
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