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The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study

INTRODUCTION: Lymphoid malignancies compose a wide spectrum of different morphologic and clinical syndromes known to vary widely throughout the world. The purpose of this study is to determine the prevalence and time trends of lymphoid malignancies. METHODS: A 15 (May 1st 1996-April 30th 2010) years...

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Autores principales: Omoti, Caroline Edijana, Nwannadi, Alexander Ikenna, Obieche, Jude Chike, Olu-Eddo, Adesuwa Noma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283024/
https://www.ncbi.nlm.nih.gov/pubmed/22368753
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author Omoti, Caroline Edijana
Nwannadi, Alexander Ikenna
Obieche, Jude Chike
Olu-Eddo, Adesuwa Noma
author_facet Omoti, Caroline Edijana
Nwannadi, Alexander Ikenna
Obieche, Jude Chike
Olu-Eddo, Adesuwa Noma
author_sort Omoti, Caroline Edijana
collection PubMed
description INTRODUCTION: Lymphoid malignancies compose a wide spectrum of different morphologic and clinical syndromes known to vary widely throughout the world. The purpose of this study is to determine the prevalence and time trends of lymphoid malignancies. METHODS: A 15 (May 1st 1996-April 30th 2010) years study of all patients who had lymph node biopsy at the Department of Haematology and Pathology, University of Benin Teaching Hospital, Benin City, Nigeria. RESULTS: The 391 patients had a male preponderance (M:F; 1.6:1). An increase in the lymphoid malignant cases was noted from 95 cases in the first 5-year interval (1996–2000) to 179 cases in the last 5-year interval (2006–2010) giving an average increase of 84.0%. Non-Hodgkins lymphoma (61.1%) and chronic lymphocytic leukaemia (18.2%) were the most frequent followed by Hodgkin's lymphoma and myeloma with equal proportions of 9.0% each. A positive correlation with a significant linear trends was obtained (r=0.1949, p<0.0001). Geographic areas at risk were found mainly in patients residing in Delta State (67.0%) which is a major oil producing state and Edo State (30.4%) where the hospital is located, both in the Niger Delta Region of Nigeria. CONCLUSION: Future research into environmental agents and genetic makeup/HLA typing of patients can be carried out.
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spelling pubmed-32830242012-02-24 The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study Omoti, Caroline Edijana Nwannadi, Alexander Ikenna Obieche, Jude Chike Olu-Eddo, Adesuwa Noma Pan Afr Med J Research INTRODUCTION: Lymphoid malignancies compose a wide spectrum of different morphologic and clinical syndromes known to vary widely throughout the world. The purpose of this study is to determine the prevalence and time trends of lymphoid malignancies. METHODS: A 15 (May 1st 1996-April 30th 2010) years study of all patients who had lymph node biopsy at the Department of Haematology and Pathology, University of Benin Teaching Hospital, Benin City, Nigeria. RESULTS: The 391 patients had a male preponderance (M:F; 1.6:1). An increase in the lymphoid malignant cases was noted from 95 cases in the first 5-year interval (1996–2000) to 179 cases in the last 5-year interval (2006–2010) giving an average increase of 84.0%. Non-Hodgkins lymphoma (61.1%) and chronic lymphocytic leukaemia (18.2%) were the most frequent followed by Hodgkin's lymphoma and myeloma with equal proportions of 9.0% each. A positive correlation with a significant linear trends was obtained (r=0.1949, p<0.0001). Geographic areas at risk were found mainly in patients residing in Delta State (67.0%) which is a major oil producing state and Edo State (30.4%) where the hospital is located, both in the Niger Delta Region of Nigeria. CONCLUSION: Future research into environmental agents and genetic makeup/HLA typing of patients can be carried out. The African Field Epidemiology Network 2012-01-20 /pmc/articles/PMC3283024/ /pubmed/22368753 Text en © Caroline Edijana Omoti et al. http://creativecommons.org/licenses/by/2.0 The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Omoti, Caroline Edijana
Nwannadi, Alexander Ikenna
Obieche, Jude Chike
Olu-Eddo, Adesuwa Noma
The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study
title The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study
title_full The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study
title_fullStr The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study
title_full_unstemmed The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study
title_short The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study
title_sort epidemiological features of lymphoid malignancies in benin city, nigeria: a 15 years study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283024/
https://www.ncbi.nlm.nih.gov/pubmed/22368753
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