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Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers

The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the...

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Detalles Bibliográficos
Autores principales: Kwon, Sojung, Lim, Hyunjung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Reproductive Medicine 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283043/
https://www.ncbi.nlm.nih.gov/pubmed/22384410
http://dx.doi.org/10.5653/cerm.2011.38.1.1
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author Kwon, Sojung
Lim, Hyunjung J.
author_facet Kwon, Sojung
Lim, Hyunjung J.
author_sort Kwon, Sojung
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description The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review.
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spelling pubmed-32830432012-03-01 Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers Kwon, Sojung Lim, Hyunjung J. Clin Exp Reprod Med Review The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review. The Korean Society for Reproductive Medicine 2011-03 2011-03-31 /pmc/articles/PMC3283043/ /pubmed/22384410 http://dx.doi.org/10.5653/cerm.2011.38.1.1 Text en Copyright © 2011. The Korean Society for Reproductive Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Kwon, Sojung
Lim, Hyunjung J.
Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
title Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
title_full Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
title_fullStr Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
title_full_unstemmed Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
title_short Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
title_sort small gtpases and formins in mammalian oocyte maturation: cytoskeletal organizers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283043/
https://www.ncbi.nlm.nih.gov/pubmed/22384410
http://dx.doi.org/10.5653/cerm.2011.38.1.1
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