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Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Society for Reproductive Medicine
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283043/ https://www.ncbi.nlm.nih.gov/pubmed/22384410 http://dx.doi.org/10.5653/cerm.2011.38.1.1 |
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author | Kwon, Sojung Lim, Hyunjung J. |
author_facet | Kwon, Sojung Lim, Hyunjung J. |
author_sort | Kwon, Sojung |
collection | PubMed |
description | The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review. |
format | Online Article Text |
id | pubmed-3283043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Korean Society for Reproductive Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-32830432012-03-01 Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers Kwon, Sojung Lim, Hyunjung J. Clin Exp Reprod Med Review The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review. The Korean Society for Reproductive Medicine 2011-03 2011-03-31 /pmc/articles/PMC3283043/ /pubmed/22384410 http://dx.doi.org/10.5653/cerm.2011.38.1.1 Text en Copyright © 2011. The Korean Society for Reproductive Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Kwon, Sojung Lim, Hyunjung J. Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers |
title | Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers |
title_full | Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers |
title_fullStr | Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers |
title_full_unstemmed | Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers |
title_short | Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers |
title_sort | small gtpases and formins in mammalian oocyte maturation: cytoskeletal organizers |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283043/ https://www.ncbi.nlm.nih.gov/pubmed/22384410 http://dx.doi.org/10.5653/cerm.2011.38.1.1 |
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