Functions of PIWI proteins in spermatogenesis

Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs) which emerged as important regulators of gene e...

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Detalles Bibliográficos
Autores principales: Bak, Chong Won, Yoon, Tae-Ki, Choi, Youngsok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Reproductive Medicine 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283061/
https://www.ncbi.nlm.nih.gov/pubmed/22384420
http://dx.doi.org/10.5653/cerm.2011.38.2.61
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author Bak, Chong Won
Yoon, Tae-Ki
Choi, Youngsok
author_facet Bak, Chong Won
Yoon, Tae-Ki
Choi, Youngsok
author_sort Bak, Chong Won
collection PubMed
description Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs) which emerged as important regulators of gene expression at the post-transcriptional or translation level. piRNAs are only present in pachytene spermatocytes and round spermatids, whereas miRNAs are expressed abundantly in male germ cells throughout spermatogenesis. This review is aimed at providing a glimpse of piRNAs and their interacting family proteins such as PIWIL1, PIWIL2, and PIWIL4 in spermatogenesis.
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spelling pubmed-32830612012-03-01 Functions of PIWI proteins in spermatogenesis Bak, Chong Won Yoon, Tae-Ki Choi, Youngsok Clin Exp Reprod Med Review Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs) which emerged as important regulators of gene expression at the post-transcriptional or translation level. piRNAs are only present in pachytene spermatocytes and round spermatids, whereas miRNAs are expressed abundantly in male germ cells throughout spermatogenesis. This review is aimed at providing a glimpse of piRNAs and their interacting family proteins such as PIWIL1, PIWIL2, and PIWIL4 in spermatogenesis. The Korean Society for Reproductive Medicine 2011-06 2011-06-30 /pmc/articles/PMC3283061/ /pubmed/22384420 http://dx.doi.org/10.5653/cerm.2011.38.2.61 Text en Copyright © 2011. The Korean Society for Reproductive Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Bak, Chong Won
Yoon, Tae-Ki
Choi, Youngsok
Functions of PIWI proteins in spermatogenesis
title Functions of PIWI proteins in spermatogenesis
title_full Functions of PIWI proteins in spermatogenesis
title_fullStr Functions of PIWI proteins in spermatogenesis
title_full_unstemmed Functions of PIWI proteins in spermatogenesis
title_short Functions of PIWI proteins in spermatogenesis
title_sort functions of piwi proteins in spermatogenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283061/
https://www.ncbi.nlm.nih.gov/pubmed/22384420
http://dx.doi.org/10.5653/cerm.2011.38.2.61
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AT yoontaeki functionsofpiwiproteinsinspermatogenesis
AT choiyoungsok functionsofpiwiproteinsinspermatogenesis

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