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Consistency-based detection of potential tumor-specific deletions in matched normal/tumor genomes

BACKGROUND: Structural variations in human genomes, such as insertions, deletion, or rearrangements, play an important role in cancer development. Next-Generation Sequencing technologies have been central in providing ways to detect such variations. Most existing methods however are limited to the a...

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Detalles Bibliográficos
Autores principales: Wittler, Roland, Chauve, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283309/
https://www.ncbi.nlm.nih.gov/pubmed/22152084
http://dx.doi.org/10.1186/1471-2105-12-S9-S21