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CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis

BACKGROUND: Granulocytes generally exert protective roles in the central nervous system (CNS), but recent studies suggest that they can be detrimental in experimental autoimmune encephalomyelitis (EAE), the most common model of multiple sclerosis. While the cytokines and adhesion molecules involved...

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Detalles Bibliográficos
Autores principales: Roy, Monica, Richard, Jean-François, Dumas, Aline, Vallières, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283467/
https://www.ncbi.nlm.nih.gov/pubmed/22269426
http://dx.doi.org/10.1186/1742-2094-9-18