In vitro and in vivo double-enhanced suicide gene therapy mediated by generation 5 polyamidoamine dendrimers for PC-3 cell line

BACKGROUND: One of the most frequently used and efficient suicide gene therapies for prostate cancer is HSV-TK/GCV system, but its application has been limited due to lack of favorable gene vector and the reduction of "bystander effect". We investigated the effect of a novel combination of...

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Detalles Bibliográficos
Autores principales: Chen, Yue, Wang, Gang, Kong, Deling, Zhang, Zhihong, Yang, Kuo, Liu, Ranlu, Zhao, Weiming, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283475/
https://www.ncbi.nlm.nih.gov/pubmed/22226139
http://dx.doi.org/10.1186/1477-7819-10-3

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