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Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications

BACKGROUND: The increased resistance of hypoxic cells to ionizing radiation is usually believed to be the primary reason for treatment failure in tumors with oxygen-deficient areas. This oxygen effect can be expressed quantitatively by the oxygen enhancement ratio (OER). Here we investigate theoreti...

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Detalles Bibliográficos
Autores principales: Wenzl, Tatiana, Wilkens, Jan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283483/
https://www.ncbi.nlm.nih.gov/pubmed/22172079
http://dx.doi.org/10.1186/1748-717X-6-171