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Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications
BACKGROUND: The increased resistance of hypoxic cells to ionizing radiation is usually believed to be the primary reason for treatment failure in tumors with oxygen-deficient areas. This oxygen effect can be expressed quantitatively by the oxygen enhancement ratio (OER). Here we investigate theoreti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283483/ https://www.ncbi.nlm.nih.gov/pubmed/22172079 http://dx.doi.org/10.1186/1748-717X-6-171 |