Enzyme Inhibitor May Offer Dual Protection against Brain Disease

Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats.

Detalles Bibliográficos
Autor principal: Choi, Charles Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Synopsis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283549/
https://www.ncbi.nlm.nih.gov/pubmed/22363209
http://dx.doi.org/10.1371/journal.pbio.1001270
Descripción
Sumario:Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats.

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