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Enzyme Inhibitor May Offer Dual Protection against Brain Disease

Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats.

Detalles Bibliográficos
Autor principal: Choi, Charles Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283549/
https://www.ncbi.nlm.nih.gov/pubmed/22363209
http://dx.doi.org/10.1371/journal.pbio.1001270
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author Choi, Charles Q.
author_facet Choi, Charles Q.
author_sort Choi, Charles Q.
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description Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats.
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spelling pubmed-32835492012-02-23 Enzyme Inhibitor May Offer Dual Protection against Brain Disease Choi, Charles Q. PLoS Biol Synopsis Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats. Public Library of Science 2012-02-21 /pmc/articles/PMC3283549/ /pubmed/22363209 http://dx.doi.org/10.1371/journal.pbio.1001270 Text en Charles Q. Choi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Synopsis
Choi, Charles Q.
Enzyme Inhibitor May Offer Dual Protection against Brain Disease
title Enzyme Inhibitor May Offer Dual Protection against Brain Disease
title_full Enzyme Inhibitor May Offer Dual Protection against Brain Disease
title_fullStr Enzyme Inhibitor May Offer Dual Protection against Brain Disease
title_full_unstemmed Enzyme Inhibitor May Offer Dual Protection against Brain Disease
title_short Enzyme Inhibitor May Offer Dual Protection against Brain Disease
title_sort enzyme inhibitor may offer dual protection against brain disease
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283549/
https://www.ncbi.nlm.nih.gov/pubmed/22363209
http://dx.doi.org/10.1371/journal.pbio.1001270
work_keys_str_mv AT choicharlesq enzymeinhibitormayofferdualprotectionagainstbraindisease