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Enzyme Inhibitor May Offer Dual Protection against Brain Disease
Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283549/ https://www.ncbi.nlm.nih.gov/pubmed/22363209 http://dx.doi.org/10.1371/journal.pbio.1001270 |
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author | Choi, Charles Q. |
author_facet | Choi, Charles Q. |
author_sort | Choi, Charles Q. |
collection | PubMed |
description | Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats. |
format | Online Article Text |
id | pubmed-3283549 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-32835492012-02-23 Enzyme Inhibitor May Offer Dual Protection against Brain Disease Choi, Charles Q. PLoS Biol Synopsis Genetic analysis in budding yeast and in cultured human astrocytes reveals that specific histone deacetylase complexes accelerate expansion mutations in DNA triplet repeats. Public Library of Science 2012-02-21 /pmc/articles/PMC3283549/ /pubmed/22363209 http://dx.doi.org/10.1371/journal.pbio.1001270 Text en Charles Q. Choi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Synopsis Choi, Charles Q. Enzyme Inhibitor May Offer Dual Protection against Brain Disease |
title | Enzyme Inhibitor May Offer Dual Protection against Brain Disease |
title_full | Enzyme Inhibitor May Offer Dual Protection against Brain Disease |
title_fullStr | Enzyme Inhibitor May Offer Dual Protection against Brain Disease |
title_full_unstemmed | Enzyme Inhibitor May Offer Dual Protection against Brain Disease |
title_short | Enzyme Inhibitor May Offer Dual Protection against Brain Disease |
title_sort | enzyme inhibitor may offer dual protection against brain disease |
topic | Synopsis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283549/ https://www.ncbi.nlm.nih.gov/pubmed/22363209 http://dx.doi.org/10.1371/journal.pbio.1001270 |
work_keys_str_mv | AT choicharlesq enzymeinhibitormayofferdualprotectionagainstbraindisease |