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Contribution of an Aged Microenvironment to Aging-Associated Myeloproliferative Disease

The molecular and cellular mechanisms of the age-associated increase in the incidence of acute myeloid leukemia (AML) remain poorly understood. Multiple studies support that the bone marrow (BM) microenvironment has an important influence on leukemia progression. Given that the BM niche itself under...

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Detalles Bibliográficos
Autores principales: Vas, Virag, Wandhoff, Corinna, Dörr, Karin, Niebel, Anja, Geiger, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283638/
https://www.ncbi.nlm.nih.gov/pubmed/22363661
http://dx.doi.org/10.1371/journal.pone.0031523