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The Bacterial Preparation OK432 Induces IL-12p70 Secretion in Human Dendritic Cells in a TLR3 Dependent Manner

Dendritic cells (DC) used in therapeutic cancer immunotherapy have to be able to stimulate T cells resulting in an immune response that can efficiently target the cancer cells. One of the critical hurdles has been the lack of IL-12p70 production when maturating the DC, which is rectified by using th...

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Detalles Bibliográficos
Autores principales:	Hovden, Arnt-Ove, Karlsen, Marie, Jonsson, Roland, Appel, Silke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283639/ https://www.ncbi.nlm.nih.gov/pubmed/22363584 http://dx.doi.org/10.1371/journal.pone.0031217

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