3, 3′-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process

3,3′-diindolylmethane (DIM), one of the active products derived from Brassica plants, is a promising antitumor agent. The present study indicated that DIM significantly induced apoptosis in U937 human leukemia cells in dose- and time-dependent manners. These events were also noted in other human leu...

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Detalles Bibliográficos
Autores principales: Gao, Ning, Cheng, Senping, Budhraja, Amit, Liu, E-Hu, Chen, Jieping, Chen, Deying, Yang, Zailin, Luo, Jia, Shi, Xianglin, Zhang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283648/
https://www.ncbi.nlm.nih.gov/pubmed/22363731
http://dx.doi.org/10.1371/journal.pone.0031783

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