Cargando…
Anti-Inflammatory Role of the cAMP Effectors Epac and PKA: Implications in Chronic Obstructive Pulmonary Disease
Cigarette smoke-induced release of pro-inflammatory cytokines including interleukin-8 (IL-8) from inflammatory as well as structural cells in the airways, including airway smooth muscle (ASM) cells, may contribute to the development of chronic obstructive pulmonary disease (COPD). Despite the wide u...
Autores principales: | Oldenburger, Anouk, Roscioni, Sara S., Jansen, Esther, Menzen, Mark H., Halayko, Andrew J., Timens, Wim, Meurs, Herman, Maarsingh, Harm, Schmidt, Martina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283666/ https://www.ncbi.nlm.nih.gov/pubmed/22363678 http://dx.doi.org/10.1371/journal.pone.0031574 |
Ejemplares similares
-
Epac as a novel effector of airway smooth muscle relaxation
por: Roscioni, Sara S, et al.
Publicado: (2011) -
Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung
por: Oldenburger, Anouk, et al.
Publicado: (2012) -
PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells
por: Roscioni, Sara S, et al.
Publicado: (2009) -
cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach
por: Ahmed, Muhammad Bilal, et al.
Publicado: (2022) -
Opposing Roles of pka and epac in the cAMP-Dependent Regulation of Schwann Cell Proliferation and Differentiation
por: Bacallao, Ketty, et al.
Publicado: (2013)