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Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain

There is increasing evidence of molecular and cellular links between Alzheimer's disease (AD) and prion diseases. The cellular prion protein, PrP(C), modulates the post-translational processing of the AD amyloid precursor protein (APP), through its inhibition of the β-secretase BACE1, and oligo...

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Detalles Bibliográficos
Autores principales:	Lewis, Victoria, Whitehouse, Isobel J., Baybutt, Herbert, Manson, Jean C., Collins, Steven J., Hooper, Nigel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283671/ https://www.ncbi.nlm.nih.gov/pubmed/22363722 http://dx.doi.org/10.1371/journal.pone.0031754

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