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Wnt Signalling Pathway Parameters for Mammalian Cells

Wnt/β-catenin signalling regulates cell fate, survival, proliferation and differentiation at many stages of mammalian development and pathology. Mutations of two key proteins in the pathway, APC and β-catenin, have been implicated in a range of cancers, including colorectal cancer. Activation of Wnt...

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Detalles Bibliográficos
Autores principales: Tan, Chin Wee, Gardiner, Bruce S., Hirokawa, Yumiko, Layton, Meredith J., Smith, David W., Burgess, Antony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283727/
https://www.ncbi.nlm.nih.gov/pubmed/22363759
http://dx.doi.org/10.1371/journal.pone.0031882