Cargando…
Matrix-Bound PAI-1 Supports Cell Blebbing via RhoA/ROCK1 Signaling
The microenvironment of a tumor can influence both the morphology and the behavior of cancer cells which, in turn, can rapidly adapt to environmental changes. Increasing evidence points to the involvement of amoeboid cell migration and thus of cell blebbing in the metastatic process; however, the cu...
Autores principales: | Cartier-Michaud, Amandine, Malo, Michel, Charrière-Bertrand, Cécile, Gadea, Gilles, Anguille, Christelle, Supiramaniam, Ajitha, Lesne, Annick, Delaplace, Franck, Hutzler, Guillaume, Roux, Pierre, Lawrence, Daniel A., Barlovatz-Meimon, Georgia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283740/ https://www.ncbi.nlm.nih.gov/pubmed/22363817 http://dx.doi.org/10.1371/journal.pone.0032204 |
Ejemplares similares
-
PAI-1 and functional blockade of SNAI1 in breast cancer cell migration
por: Fabre-Guillevin, Elizabeth, et al.
Publicado: (2008) -
Loss of p53 promotes RhoA–ROCK-dependent cell migration and invasion in 3D matrices
por: Gadea, Gilles, et al.
Publicado: (2007) -
Cooperative Anti-Invasive Effect of Cdc42/Rac1 Activation and ROCK Inhibition in SW620 Colorectal Cancer Cells with Elevated Blebbing Activity
por: de Toledo, Marion, et al.
Publicado: (2012) -
Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing
por: Mistriotis, Panagiotis, et al.
Publicado: (2019) -
RhoA, ROCK-1, and ROCK-2 Gene Expression and Polymorphisms in Cholesteatoma Patients
por: Görür, Kemal, et al.
Publicado: (2021)