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Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report
A large cell neuroendocrine carcinoma (LCNEC) of the thymus is a very rare malignant tumor that has a very poor prognosis. The detailed clinical features of LCNEC are still unknown, including the long term prognoses and the definitive modalities of the treatment for LCNEC of the thymus. We are repor...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Thoracic and Cardiovascular Surgery
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283788/ https://www.ncbi.nlm.nih.gov/pubmed/22363912 http://dx.doi.org/10.5090/kjtcs.2012.45.1.60 |
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author | Yoon, Yong Han Kim, Jae Ho Kim, Kwang Ho Baek, Wan Ki Lee, Hyun Kyu Lee, Moon Hee Lee, Kyung Hee Kim, Lucia |
author_facet | Yoon, Yong Han Kim, Jae Ho Kim, Kwang Ho Baek, Wan Ki Lee, Hyun Kyu Lee, Moon Hee Lee, Kyung Hee Kim, Lucia |
author_sort | Yoon, Yong Han |
collection | PubMed |
description | A large cell neuroendocrine carcinoma (LCNEC) of the thymus is a very rare malignant tumor that has a very poor prognosis. The detailed clinical features of LCNEC are still unknown, including the long term prognoses and the definitive modalities of the treatment for LCNEC of the thymus. We are reporting 2 cases of an enlarged LCNEC of the thymus, both of which were diagnosed and treated by surgical resection followed by postoperative adjuvant chemoradiation therapy. Although recurrences and metastases of the LCNEC were noticed 1 and 4 years postoperatively for each case, aggressive surgical resection and adjuvant chemoradiation therapy may be helpful for a patient's long term survival. |
format | Online Article Text |
id | pubmed-3283788 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Korean Society for Thoracic and Cardiovascular Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-32837882012-02-23 Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report Yoon, Yong Han Kim, Jae Ho Kim, Kwang Ho Baek, Wan Ki Lee, Hyun Kyu Lee, Moon Hee Lee, Kyung Hee Kim, Lucia Korean J Thorac Cardiovasc Surg Case Report A large cell neuroendocrine carcinoma (LCNEC) of the thymus is a very rare malignant tumor that has a very poor prognosis. The detailed clinical features of LCNEC are still unknown, including the long term prognoses and the definitive modalities of the treatment for LCNEC of the thymus. We are reporting 2 cases of an enlarged LCNEC of the thymus, both of which were diagnosed and treated by surgical resection followed by postoperative adjuvant chemoradiation therapy. Although recurrences and metastases of the LCNEC were noticed 1 and 4 years postoperatively for each case, aggressive surgical resection and adjuvant chemoradiation therapy may be helpful for a patient's long term survival. Korean Society for Thoracic and Cardiovascular Surgery 2012-02 2012-02-07 /pmc/articles/PMC3283788/ /pubmed/22363912 http://dx.doi.org/10.5090/kjtcs.2012.45.1.60 Text en © The Korean Society for Thoracic and Cardiovascular Surgery. 2012. All right reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Yoon, Yong Han Kim, Jae Ho Kim, Kwang Ho Baek, Wan Ki Lee, Hyun Kyu Lee, Moon Hee Lee, Kyung Hee Kim, Lucia Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report |
title | Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report |
title_full | Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report |
title_fullStr | Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report |
title_full_unstemmed | Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report |
title_short | Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report |
title_sort | large cell neuroendocrine carcinoma of the thymus: a two-case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283788/ https://www.ncbi.nlm.nih.gov/pubmed/22363912 http://dx.doi.org/10.5090/kjtcs.2012.45.1.60 |
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